In vivo sites and cellular mechanisms of T reg cell–mediated suppression
نویسندگان
چکیده
Regulatory CD4 T (T reg) cells control immune responses to self-antigens and pathogens. However, where T reg cells act to curtail effector T cells in vivo and what stage of effector T cell activation or differentiation is targeted by T reg cells remain unknown. Furthermore, a requirement for direct effector T cell-T reg cell contact in vivo has not been ascertained. Varying answers to these important questions have been provided by several new studies.
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عنوان ژورنال:
- The Journal of Experimental Medicine
دوره 203 شماره
صفحات -
تاریخ انتشار 2006